听力与言语-语言病理学

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医学伦理学

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  • Temporal coding of sensation: mimicking taste quality with electrical stimulation of the brain.

    abstract::Two experiments suggested that the temporal pattern of a taste response in the brain can convey meaningful information. In Experiment 1, rats avoided lick-contingent electrical stimulation of the nucleus of the solitary tract (NTS; the first synaptic relay for taste) when the temporal pattern of pulses mimicked the el...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.6.1423

    authors: Di Lorenzo PM,Hallock RM,Kennedy DP

    更新日期:2003-12-01 00:00:00

  • The role of perirhinal cortex in visual discrimination learning for visual secondary reinforcement in rats.

    abstract::Perirhinal cortex in monkeys has been thought to be involved in visual associative learning. The authors examined rats' ability to make associations between visual stimuli in a visual secondary reinforcement task. Rats learned 2-choice visual discriminations for secondary visual reinforcement. They showed significant ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.6.1318

    authors: Eacott MJ,Norman G,Gaffan EA

    更新日期:2003-12-01 00:00:00

  • The ontogeny of human learning in delay, long-delay, and trace eyeblink conditioning.

    abstract::The ontogeny of associative learning in delay (750-ms conditional stimulus [CS], 650-ms interstimulus interval [ISI]), long-delay (1,350-ms CS, 1,250-ms ISI), and trace (750-ms CS, 500-ms trace interval, 1,250-ms ISI) eyeblink conditioning was examined in 5-month-old human infants and adults. Infants and adults showed...

    journal_title:Behavioral neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1037/0735-7044.117.6.1196

    authors: Herbert JS,Eckerman CO,Stanton ME

    更新日期:2003-12-01 00:00:00

  • Receptor contributions to configural and elemental odor mixture perception.

    abstract::Odor mixture perception can be configural (the mixture is qualitatively different from the components) or elemental (the components are recognizable). Some have argued that configural properties are dependent on chemical similarity and possible overlap at the receptor level. The authors show that a binary mixture in w...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.5.1108

    authors: Kay LM,Lowry CA,Jacobs HA

    更新日期:2003-10-01 00:00:00

  • Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running.

    abstract::The hippocampus is important for the acquisition of new memories. It is also one of the few regions in the adult mammalian brain that can generate new nerve cells. The authors tested the hypothesis that voluntary exercise increases neurogenesis and enhances spatial learning in mice selectively bred for high levels of ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.5.1006

    authors: Rhodes JS,van Praag H,Jeffrey S,Girard I,Mitchell GS,Garland T Jr,Gage FH

    更新日期:2003-10-01 00:00:00

  • Neonatal handling reduces the number of cells in the locus coeruleus of rats.

    abstract::Neonatal handling induces long-lasting effects on behaviors and stress responses. The objective of the present study was to analyze the effects of neonatal handling (from the 1st to the 10th day after delivery) on the number of cells and volume of locus coeruleus (LC) nucleus in male and female rats at 4 different age...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.5.894

    authors: Lucion AB,Pereira FM,Winkelman EC,Sanvitto GL,Anselmo-Franci JA

    更新日期:2003-10-01 00:00:00

  • Behavioral depression during cocaine withdrawal is associated with decreased spontaneous activity of ventral tegmental area dopamine neurons.

    abstract::Withdrawal from an escalating-dose, bingelike regimen of cocaine administration in rats produced significantly depressed levels of locomotor activity during the nocturnal portion of the day-night cycle. This effect was observed during the first 48 hr of testing. Extracellular single-unit recordings of ventral tegmenta...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.4.860

    authors: Koeltzow TE,White FJ

    更新日期:2003-08-01 00:00:00

  • Effects of passive-avoidance training on sleep-wake state-specific activity in the basolateral and central nuclei of the amygdala.

    abstract::This study examined the effects of intense emotional learning on the sleep-wake state-specific electroencephalographic (EEG) activities of the basolateral (BLA) and central (CeA) nuclei of the amygdala. Rats were trained on a passive-avoidance learning (PAL) protocol that was followed by 6 hr of undisturbed polygraphi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.4.751

    authors: Mavanji V,Siwek DF,Patterson EH,Spoley EE,Datta S

    更新日期:2003-08-01 00:00:00

  • Novel objects in a holeboard probe the role of the locus coeruleus in curiosity: support for two modes of attention in the rat.

    abstract::Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.3.621

    authors: Mansour AA,Babstock DM,Penney JH,Martin GM,McLean JH,Harley CW

    更新日期:2003-06-01 00:00:00

  • Selective effects of triazolam on memory for emotional, relative to neutral, stimuli: differential effects on gist versus detail.

    abstract::Benzodiazepines are known to reduce learning and memory performance, presumably through their facilitation of GABAergic neurotransmission, but the effects of these drugs specifically on memory for emotional material has not been addressed in humans. The effects of a benzodiazepine (triazolam, 0.25 mg) on nonincidental...

    journal_title:Behavioral neuroscience

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1037/0735-7044.117.3.517

    authors: Buchanan TW,Karafin MS,Adolphs R

    更新日期:2003-06-01 00:00:00

  • The evolution of sex differences in spatial ability.

    abstract::It is widely believed that male mammals have better spatial ability than females. A large number of evolutionary hypotheses have been proposed to explain these differences, but few species have been tested. The authors critically review the proposed evolutionary explanations for sex differences in spatial cognition an...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/0735-7044.117.3.403

    authors: Jones CM,Braithwaite VA,Healy SD

    更新日期:2003-06-01 00:00:00

  • Effects of D-cycloserine on extinction of conditioned freezing.

    abstract::The present study tested the prediction that D-cycloserine (DCS), a partial N-methyl-D-aspartate agonist, would facilitate extinction of conditioned freezing in male Sprague-Dawley rats. Rats received 5 light-shock pairings (conditioning). The following day, rats received 6 light-alone presentations (extinction traini...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.2.341

    authors: Ledgerwood L,Richardson R,Cranney J

    更新日期:2003-04-01 00:00:00

  • Configurational and nonconfigurational interactions between odorants in binary mixtures.

    abstract::Studies on odor mixture perception suggest that although odor components can often be identified in mixtures, mixtures can also give rise to novel perceptual qualities that are not present in the components. Using an olfactory habituation task, the authors evaluated how the perceptual similarity between components in ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.2.236

    authors: Wiltrout C,Dogra S,Linster C

    更新日期:2003-04-01 00:00:00

  • Modulation of memory consolidation for olfactory learning by reversible inactivation of the basolateral amygdala.

    abstract::The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.117.1.184

    authors: Kilpatrick L,Cahill L

    更新日期:2003-02-01 00:00:00

  • Sex-related differences in spatial divided attention and motor impulsivity in rats.

    abstract::The acquisition and performance of a self-paced test of spatial divided attention linked with frontal cortex function were assessed in postpubertal (> 60 days) normal or gonadectomized male and female rats. Males were more accurate at detecting relatively brief visual stimuli than females, but this difference was elim...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.117.1.76

    authors: Jentsch JD,Taylor JR

    更新日期:2003-02-01 00:00:00

  • Air-stepping in neonatal rats: A comparison of L-dopa injection and olfactory stimulation.

    abstract::The kinematic parameters of air-stepping induced by 2 methods known to elicit locomotion (olfactory stimulation vs. L-dopa injection) were compared in 3-day-old rats. In the 1st stage, suspended pups were induced to step with an olfactory stimulus of soiled shavings from the nest. In the 2nd stage, they received a sub...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.6.1014

    authors: Jamon M,Maloum I,Riviere G,Bruguerolle B

    更新日期:2002-12-01 00:00:00

  • The union of the state: myoclonic twitching is coupled with nuchal muscle atonia in infant rats.

    abstract::Active sleep (AS), as measured by the occurrence of myoclonic twitching (MT), is the most prevalent behavioral state in newborn rats. Historically, AS has been considered a developmental precursor of REM sleep, but recently this idea has been questioned. In the present study, the authors assess, in 2-, 5-, and 8-day-o...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.5.912

    authors: Karlsson KA,Blumberg MS

    更新日期:2002-10-01 00:00:00

  • Ventral tegmental area dopamine neurons mediate the shock sensitization of acoustic startle: a potential site of action for benzodiazepine anxiolytics.

    abstract::Dopamine (DA)-containing neurons in the ventral tegmental area (VTA) are thought to play an important role in fear motivation. The primary objective of the present study was to determine the connection between DA D2, gamma aminobutyric acid (GABA)A, and benzodiazepine receptors in the VTA and footshock-associated emot...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Gifkins A,Greba Q,Kokkinidis L

    更新日期:2002-10-01 00:00:00

  • Conditioned Fos expression following morphine-paired contextual cue exposure is environment specific.

    abstract::Environmental cues associated with drug administration elicit neural activation in circuits involved in cognitive processes and emotional regulation. An important question is whether the neural activation observed is specific to the drug-paired environment or is due to a generalized activation induced by previous drug...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.4.727

    authors: Schroeder BE,Kelley AE

    更新日期:2002-08-01 00:00:00

  • Dissociation of conditioned locomotion and Fos induction in response to stimuli formerly paired with cocaine.

    abstract::A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Hotsenpiller G,Horak BT,Wolf ME

    更新日期:2002-08-01 00:00:00

  • Impaired learning of a color reversal task after NMDA receptor blockade in the pigeon (Columba livia) associative forebrain (neostriatum caudolaterale).

    abstract::The neostriatum caudolaterale (NCL) in the pigeon (Columba livia) forebrain is a multisensory associative area and a functional equivalent to the mammalian prefrontal cortex (PFC). To investigate the role of N-methyl-D-aspartate (NMDA) receptors in the NCL for learning flexibility, the authors trained pigeons in a col...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.4.523

    authors: Lissek S,Diekamp B,Güntürkün O

    更新日期:2002-08-01 00:00:00

  • Opioids and attachment in rhesus macaque (Macaca mulatta) abusive mothers.

    abstract::This study investigated the role of the endogenous opioid system in maternal and affiliative behavior of group-living rhesus macaque (Macaca mulatta) mothers with a history of abusive parenting. Eighteen mothers received an injection of the opioid antagonist naltrexone or saline for 5 days per week for the first 4 wee...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.3.489

    authors: Graves FC,Wallen K,Maestripieri D

    更新日期:2002-06-01 00:00:00

  • Tonic and phasic activation and arousal effects as a function of feedback in repetitive-choice reaction time tasks.

    abstract::This study examines the effects of positive and negative feedback on performance during choice reaction time tasks to assess whether they differentially affect phasic arousal and tonic activation. Participants (N = 96) received either no feedback or signals of reward, punishment, or both during a semantic and a visuos...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.3.397

    authors: De Brabander B,Declerck CH,Boone C

    更新日期:2002-06-01 00:00:00

  • Long-term study of chronic oral aluminum exposure and spatial working memory in rats.

    abstract::The authors report an effort to advance animal models that mimic the cognitive decline of Alzheimer's disease. Rats were trained and repeatedly tested in a spatial delayed matching-to-position paradigm in the water maze, with the location of the submerged platform changing between, but not within, days. After Trial 1 ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.2.351

    authors: von Linstow Roloff E,Platt B,Riedel G

    更新日期:2002-04-01 00:00:00

  • Impairments in negative patterning, but not simple discrimination learning, in rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis.

    abstract::Rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis (NBM) and sham-operated rats were trained in either a simple discrimination paradigm assessing simple association learning or a negative patterning paradigm assessing configural association learning. In the simple discrimination task, rats were r...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.2.241

    authors: Butt AE,Noble MM,Rogers JL,Rea TE

    更新日期:2002-04-01 00:00:00

  • Medial dorsal thalamic lesions impair blocking and latent inhibition of the conditioned eyeblink response in rats.

    abstract::The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.2.276

    authors: Nicholson DA,Freeman JH Jr

    更新日期:2002-04-01 00:00:00

  • Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus.

    abstract::Conditioned inhibition (CI) of the rat eyeblink response and the neuronal correlates of CI in the cerebellar interpositus nucleus were examined in the present study. In Experiment 1, CI was established with a novel, 3-group design. In Experiment 2, neuronal activity in the anterior interpositus nucleus was recorded du...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Nicholson DA,Freeman JH Jr

    更新日期:2002-02-01 00:00:00

  • Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole, but not the D1 agonist SKF 38393 or the D2 antagonist haloperidol.

    abstract::The authors have recently shown that attenuation of an external response feedback leads to excessive lever-pressing that is not associated with attempts to collect reward, and they have suggested that this may be an analogue to "unreasonable" excessive behavior characteristic of obsessive-compulsive disorder. The pres...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.115.6.1291

    authors: Joel D,Avisar A,Doljansky J

    更新日期:2001-12-01 00:00:00

  • Reactivation of hippocampal ensemble activity patterns in the aging rat.

    abstract::In young rats, the pattern of neuronal ensemble activity correlations expressed among hippocampal pyramidal cells during behavior persists during subsequent quiet wakefulness and slow-wave sleep, a process that may facilitate the consolidation of episodic memories. The present study explored the hypothesis that age-re...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Gerrard JL,Kudrimoti H,McNaughton BL,Barnes CA

    更新日期:2001-12-01 00:00:00

  • The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta).

    abstract::Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.115.5.971

    authors: Bussey TJ,Wise SP,Murray EA

    更新日期:2001-10-01 00:00:00

  • Functional recovery of taste sensitivity to sodium chloride depends on regeneration of the chorda tympani nerve after transection in the rat.

    abstract::Chorda tympani nerve (CT) transection (CTX) raises sodium chloride (NaCl) taste detection threshold, but the effect of CT regeneration on NaCl threshold is unknown. This experiment examined whether CT regeneration supports normal NaCl threshold in the rat. Thresholds were measured with a 2-lever operant procedure. Thr...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Kopka SL,Spector AC

    更新日期:2001-10-01 00:00:00

  • Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster).

    abstract::Male prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this behavior is regulated by the neuropeptide vasopressin (AVP). The authors report that AVP in the lateral septum is important for pair bond formation. Administration of an AVP V1a receptor antagonist in the lateral se...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.115.4.910

    authors: Liu Y,Curtis JT,Wang Z

    更新日期:2001-08-01 00:00:00

  • Functional disconnection of a prefrontal cortical-dorsal striatal system disrupts choice reaction time performance: implications for attentional function.

    abstract::This series of experiments investigated the role of a prefrontal cortical-dorsal striatal circuit in attention, using a continuous performance task of sustained and spatially divided visual attention. A unilateral excitotoxic lesion of the medial prefrontal cortex and a contralateral lesion of the medial caudate-putam...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.115.4.812

    authors: Christakou A,Robbins TW,Everitt BJ

    更新日期:2001-08-01 00:00:00

  • Conditioned brain-stimulation reward attenuates the acoustic startle reflex in rats.

    abstract::The acoustic startle reflex (ASR) in rats is attenuated by a light paired with food or, in humans, by "pleasant" pictures. Rats were trained to barpress for lateral hypothalamus (LH) stimulation. ASR amplitudes were then measured at 4 intensities, with or without a light. Control rats that did not receive brain-stimul...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Steidl S,Li L,Yeomans JS

    更新日期:2001-06-01 00:00:00

  • Hippocampal growth and maintenance depend on food-caching experience in juvenile mountain chickadees (Poecile gambeli).

    abstract::This experiment investigated the development of caching behavior and the hippocampus (HF) in postfledging mountain chickadees (Poecile gambeli). From Days 35 to 53, the number of seeds stored increased but the proportion recovered did not. Birds that stored and recovered during 3 or more trials had significantly enlar...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.115.3.614

    authors: Clayton NS

    更新日期:2001-06-01 00:00:00

  • Exploration, anxiety, and spatial memory in transgenic anophthalmic mice.

    abstract::Contradictory results are found in the literature concerning the role of vision in the perception of space or in spatial navigation, in part because of the lack of murine models of total blindness used so far. The authors evaluated the spatial abilities of anophthalmic transgenic mice. These mice did not differ qualit...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Buhot MC,Dubayle D,Malleret G,Javerzat S,Segu L

    更新日期:2001-04-01 00:00:00

  • Human fear conditioning is related to dopaminergic and serotonergic biological markers.

    abstract::Biological markers for acquisition and extinction of fear conditioning were studied in 40 individuals selected for displaying either good or poor acquisition of fear conditioning. as estimated by the skin conductance response. Participants with a short serotonin transporter (5-HTT) promoter allele or low monoamine oxi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Garpenstrand H,Annas P,Ekblom J,Oreland L,Fredrikson M

    更新日期:2001-04-01 00:00:00

  • Head direction, place, and movement correlates for cells in the rat retrosplenial cortex.

    abstract::The retrosplenial cortex is strongly connected with brain regions involved in spatial signaling. To test whether it also codes space, single cells were recorded while rats navigated in an open field. As in earlier work (L. L. Chen, L. H. Lin, C. A. Barnes, & B. L. McNaughton, 1994; L. L. Chen, L. H. Lin, E. J. Green, ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.115.1.3

    authors: Cho J,Sharp PE

    更新日期:2001-02-01 00:00:00

  • Differential sensitivity to the wake-promoting actions of norepinephrine within the medial preoptic area and the substantia innominata.

    abstract::Mapping studies were conducted to delineate the site(s) of action for the arousal-enhancing actions of norepinephrine (NE) within the basal forebrain region encompassing the medial preoptic area (MPOA) and the substantia innominata (SI). Varying doses of NE, the beta-agonist, isoproterenol, or the alpha1-agonist, phen...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.115.1.165

    authors: Berridge CW,O'Neill J

    更新日期:2001-02-01 00:00:00

  • A peripheral, intracerebral, or intrathecal administration of an opioid receptor antagonist blocks illness-induced hyperalgesia in the rat.

    abstract::We used the tail-flick response of rats to study the role of opioid receptors in illness-induced hyperalgesia. An intraperitoneal injection of lithium chloride (LiCl) produced hyperalgesia that was blocked in a dose-dependent manner by subcutaneous injection of the opioid antagonist naloxone. Neither hyperalgesia nor ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.114.6.1183

    authors: McNally GP,Johnston IN,Westbrook RF

    更新日期:2000-12-01 00:00:00

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